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IL-1 receptor type I (human):Fc (human), (recombinant)

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Alternative Name	IL-1RI, Interleukin-1 receptor type I, CD121a
Concentration	1mg/ml after reconstitution.
Endotoxin Content	<0.1EU/µg purified protein (LAL test; Lonza).
Formulation	Lyophilized. Contains PBS.
MW	~83kDa (SDS-PAGE).
Purity	≥90% (SDS-PAGE)
Reconstitution	Reconstitute with 50µl sterile water. PBS containing at least 0.1% BSA should be used for further dilutions.
Source	Produced in HEK 293 cells. Human IL-1RI (interleukin-1 receptor type I) (aa 21-336) is fused to the Fc portion of human IgG1.
Specificity	Binds to human IL-1 (interleukin-1).
Technical Info / Product Notes	Historical data has shown that IL-1 receptor blocks IL-1 activity.
UniProt ID	P14778

Use/Stability	Stable for at least 6 months after receipt when stored at -20°C.
Handling	Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20°C.
Short Term Storage	+4°C
Long Term Storage	-20°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

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Alternative Name	Thy-1 (RLE mutant)
Purity	≥90% (SDS-PAGE)
Source	Produced in HEK 293 cells. The extracellular domain of mutated hThy-1, hThy-1 (RLE) (aa 20-130), is fused to the Fc portion of human IgG1. The integrin binding sequence RLD of hThy-1 has been changed to RLE abolishing the binding of integrins.

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