Home Shop IL-1β (human), (recombinant) (cell culture grade)

IL-1β (human), (recombinant) (cell culture grade)

Already have an account?

Potent immunomodulator

Potent immunomodulator. Mediates a wide range of immune and inflammatory responses including the activation of B and T cells.

Shipping: Available products typically ship within 24/48h, via priority shipping.

Do you need support? Contact Customer Service or Technical Support.

Online Account
Access or Create Your Account

Alternative Name	IL-1F2, Interleukin-1β
Biological Activity	Exerts in vitro biological activity in the range of 0.1-10ng/ml.
CAS	97599-21-8
Endotoxin Content	<1EU/µg protein.
Formulation	Lyophilized. Salt-free.
MI	14: 4993
MW	~17kDa.
Purity	≥97% (SDS-PAGE)
Reconstitution	Reconstitute with water, PBS or aqueous buffer to a concentration of 100µg/ml. For further dilution carrier protein (~1%) should be added to avoid loss of bioactivity.
Source	Produced in E. coli.
Specific Activity	≥1×10⁷U/mg protein. Determined by proliferation assay using human TF-1 (T. Kitamura, et al.; Int. Immunol. 3, 571 (1991)). The ED₅₀ for this effect is typically 0.2-2ng/ml. Results were compared with the international IL-1 reference standard preparation (WHO 86/680, NIBSC).
UniProt ID	P01584

Handling	Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20°C.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Interleukin-1β Induces mtDNA Release to Activate Innate Immune Signaling via cGAS-STING: Aarreberg, L. D., Esser-Nobis, K., et al.; Mol. Cell 74, 801 (2019), Abstract
An unexpected effect of TNF-α on F508del-CFTR maturation and function: S. Bitam, et al.; F1000Res 4, 218 (2015), Abstract — Full Text
Expression of an uncleavable N-terminal RasGAP fragment in insulin-secreting cells increases their resistance toward apoptotic stimuli without affecting their glucose-induced insulin secretion: J.Y. Yang, et al.; J. Biol. Chem. 280, 32835 (2005), Abstract

Datasheet, Manuals, SDS & CofA

Please enter the lot number as featured on the product label

Lot No. :

Enzo Life Science provides GHS Compliant SDS

If your language is not available please fill out the SDS request form