- Highly sensitive, detecting as low as 34.2 pg/ml IGF-1
- Broad dynamic range suitable for use with a variety of samples
- High throughput format with results for up to 40 samples in duplicate in just 4 hours
- Fully quantitative results that surpass semi-quantitative Western blot analysis
The IGF-1 (human), ELISA kit is a colorimetric immunometric enzyme-linked immunosorbent assay kit with results in 4 hours. Absorbance is read at 450 nm. This kit offers ultra-sensitive measurement of as little as 34.2 pg/ml of IGF-1.
Insulin-like growth factor-I (IGF-I) is a polypeptide hormone similar in structure to insulin. It is involved in regulation of neuronal growth and development in the central and peripheral nervous system. IGF-1 is a potent inhibitor of apoptosis in neurons, and activates the Akt signaling pathway via the IGF-1R and Insulin receptors. The IGF-1R acts as a receptor for IGF-1 and the related IGF-2, and is subject to autophosphorylation on multiple tyrosine residues that regulate receptor activation and assembly of signal transduction complexes.
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