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Cell cycle non-specific alkylating agent belonging to the class of anticancer drugs called nitrogen mustards. Strucural analog of cyclophosphamide. The drug is activated in human liver by a 4-hydroxylation reaction catalyzed by multiple cytochrome P-450 enzymes [1]. The product is 4-hydroxy IF, which ultimately yields the alkylating mustard isophophoramide [2]. Cytostatic agent.
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RUO – Research Use Only |
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