Home Shop IFN-γ (human), (recombinant)

IFN-γ (human), (recombinant)

ENZ-PRT141

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Human interferon-γ (IFN-γ) is an inflammatory cytokine secreted by T lymphocytes and natural killer (NK) cells. IFN-γ is primarily characterized as an activator of macrophages, and is the principle cytokine produced by CD4+ inflammatory TH1 cells. IFN-γ signals are transmitted via a heterodimeric IFNGR1/IFNGR2 receptor which activates transcription of immunoregulatory genes via the Jak/Stat pathway.

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Product Details

Alternative Name	Interferon-γ
Endotoxin Content	≤1 EU/µg
Formulation	Lyophilized from 10mM sodium phosphate, pH 7.4.
MW	~16.8 kDa
Purity	≥98% (SDS-PAGE gel & HPLC)
Reconstitution	Reconstitute in sterile water at 1 mg/mL. Do not vortex.
Source	Produced in E.coli.
UniProt ID	P01579

Handling & Storage

Handling	Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -80°C. For long term storage, it is recommended to dilute to working aliquots in a 0.1% BSA solution.
Short Term Storage	-20°C
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

ERH regulates type II interferon immune signaling through post-transcriptional regulation of JAK2 mRNA: Soderholm, A., Vunjak, M., et al.; Nucleic Acids Res. 53, gkaf545 (2025), Abstract
ERH regulates type II interferon immune signaling through post-transcriptional regulation ofJAK2mRNA: Soderholm, A., Vunjak, M., et al.; bioRxiv , (2024)
MIF confers survival advantage to pancreatic CAFs by suppressing interferon pathway-induced p53-dependent apoptosis: Suresh, V., Dash, P., et al.; FASEB J. 36, e22449 (2022), Abstract
Autophagy in T cells from aged donors is maintained by spermidine and correlates with function and vaccine responses: Alsaleh, G., Panse, I., et al.; Elife 9, (2020), Abstract

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IFN-γ (human), (recombinant)

ENZ-PRT141

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Certificate of Analysis

SDS

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