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Hydroxytyrosol . acetate

ALX-350-404

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Antioxidant

Antioxidant comparable to resveratrol (Prod. No. BML-FR104). Is converted to hydroxytyrosol through hydrolysis by esterases. Reaches full oxygen radical absorbance capacity (ORAC) when converted to free hydoxytyrosol. ORAC values of hydroxytyrosol are about 50% higher than resveratrol, 10-fold higher than L(+)-ascorbic acid and 4-fold higher than (-)-epicatechin. Has been shown to have anticancer and antiviral effects.
Antibacterial at 400µg/mL against Streptococcus pyogenes, Staphylococcus aureus, Escherichia coli and Klebsiella pneumoniae.

Hydroxytyrosol-acetate is a small-molecule phenolic compound found in the leaves and fruits of olive (Olea eurolaea). It is a metabolite of oleuropein (Ole), one of the major polyphenolic components of olive products.

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Product Details

Alternative Name	HTS, 2-(3,4-Dihydroxyphenyl)-ethyl acetate
Appearance	White to off-white powder.
CAS	69039-02-7
Formula	C₁₀H₁₂O₄
MW	196.2
Purity	≥98% (HPLC)
Solubility	Freely soluble in organic solvents; slightly soluble in water (10mg/ml).
Source	Synthetic

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended.
Handling	Protect from light.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Identification and Evaluation of Olive Phenolics in the Context of Amine Oxidase Enzyme Inhibition and Depression: In Silico Modelling and In Vitro Validation: Karagiannis, T., Ververis, K., et al.; Molecules 29, (2024), Abstract
Synergistic antibacterial effects of polyphenolic compounds from olive mill wastewater: A. Tafesh, et al.; Evid. Based Complement. Alternat. Med. 2011, 431021 (2011), Abstract — Full Text
Effects of olive oil polyphenols on fatty acid synthase gene expression and activity in human colorectal cancer cells: M. Notarnicola, et al.; Genes Nutr. 6, 63 (2011), Abstract — Full Text
Hydroxytyrosol inhibits the proliferation of human colon adenocarcinoma cells through inhibition of ERK1/2 and cyclin D1.: G. Corona et al.; JP. Mol. Nutr. Food Res. 53, 897 (2009), Abstract
The protective effects of hydroxytyrosol against UVB-induced DNA damage in HaCaT cells.: W. Guo et al.; Phytother. Res. 24, 352 (2009), Abstract
Mechanism of the antiviral effect of hydroxytyrosol on influenza virus appears to involve morphological change of the virus.: K. Yamada et al.; Antiviral Res. 83, 35 (2009), Abstract
Anti-proliferative and apoptotic effects of oleuropein and hydroxytyrosol on human breast cancer MCF-7 cells.: J. Han et al.; Cytotechnology 59, 45 (2009), Abstract
Metabolism of the olive oil phenols hydroxytyrosol, tyrosol, and hydroxytyrosyl acetate by human hepatoma HepG2 cells.: R. Mateos et al.; J. Agric. Food. Chem. 53, 9897 (2005), Abstract

Related Products

Resveratrol

BML-FR104

Antioxidant. SIRT1 activator.

38 citations

Alternative Name	trans-3,4′,5-Trihydroxystilbene
CAS	501-36-0
Couple Type	Activator, Inhibitor, Ligand
Purity	≥98% (HPLC)

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Hydroxytyrosol . acetate

ALX-350-404

Product Details

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