HSP65 (low endotoxin) (M. bovis), (recombinant)

Hsp65, a 65 kDa protein isolated from Mycobacterium bovis BCG, is a member of the hsp60 family of heat shock proteins. Sequence comparison of Hsp65 from different mycobacterium strains showed that the protein sequence of M. bovis BCG is identical to that of M. tuberculosis, and very similar to that of M. leprae, the pathogens that cause tuberculosis and tuberculoid leprosy, respectively. M. bovis BCG Hsp65 was identified as the immunodominant antigen during mycobacterial diseases and vaccination.