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HSP104 polyclonal antibody

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Alternative Name	Heat shock protein 104
Application	WB
Application Notes	Detects a band of ~104kDa (yeast). Does not cross-react with HSP100 from prokaryotes, nor certain plants or insects including Drosophila.
Crossreactivity	Does not cross-react with HSP100 from prokaryotes, nor certain plants or insects including Drosophila.
Formulation	Liquid. Contains 0.05% sodium azide.
Host	Rabbit
Immunogen	Synthetic peptide corresponding to aa 894-908 (D894DDNEDSMEIDDDLD908) of C-terminal S. cerevisiae HSP104 (heat shock protein 104).
Recommendation Dilutions/Conditions	Western Blot (1:5,000)Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application.
Species Reactivity	Yeast
UniProt ID	P31539
Worry-free Guarantee	This antibody is covered by our Worry-Free Guarantee.

Regulatory Status	RUO – Research Use Only

Rbs1 protein, involved in RNA polymerase III complex assembly in the yeast Saccharomyces cerevisiae, induces a Gcn4 response and forms aggregates when overproduced: I. Rudzińska, et al.; Gene 809, 146034 (2022), Abstract
Hsp104 is a highly conserved protein with two essential nucleotide- binding sites: D.A. Parsell, et al.; Nature 353, 270 (1991), Abstract

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