Unique high definition blue IHC chromogen for HRP-activated development.
HIGHDEF® blue IHC chromogen (HRP) is intended to be used in conjunction with horseradish peroxidase (HRP)-based immunostaining or in situ hybridization (ISH) systems.
Application Note
Tumor Phenotyping and Immune Cell Regulation using Multiplex IHC
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Product Details
Application |
IHC, ISH (in situ hybridization) |
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Contents |
HIGHDEF® blue IHC chromogen (HRP) substrate buffer and chromogen, Empty mixing bottle |
Technical Info / Product Notes |
The HIGHDEF® blue IHC chromogen (HRP) is a substrate-chromogen system designed to be used for either immunohistochemistry (IHC) or ISH when utilizing horseradish peroxidase. HIGHDEF® blue IHC chromogen (HRP) produces a sharply contrasting billiant blue color that can easily be distinguished from other stains. |
Handling & Storage
Long Term Storage |
+4°C |
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Shipping |
Blue Ice |
Regulatory Status |
RUO – Research Use Only |
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- Immunohistochemical study of neural stem cell lineage markers in canine brains, gliomas, and a glioma cell line: K. Yoshida, et al.; Vet. Pathol. 60, 35 (2023), Abstract
- Plasma cells, plasmablasts, and AID+/CD30+ B lymphoblasts inside and outside germinal centres: details of the basal light zone and the outer zone in human palatine tonsils: B.S. Steiniger, et al.; Histochem. Cell Biol. 154, 55 (2020), Abstract — Full Text
- Characterization of non-hormone expressing endocrine cells in fetal and infant human pancreas: A.S.M. Moin, et al.; Front. Endocrinol. 9, 791 (2019), Abstract — Full Text
- CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy: W. Wang, et al.; Nature 569, 270 (2019), Abstract — Full Text
- Age-and disease-dependent increase of the mitophagy marker phospho-ubiquitin in normal aging and Lewy body disease: X. Hou, et al.; Autophagy 14, 1404 (2018), Abstract — Full Text
- Platelet lysate-derived neuropeptide y influences migration and angiogenesis of human adipose tissue-derived stromal cells: R. Businaro, et al.; Sci. Rep. 8, 14365 (2018), Abstract — Full Text
- Altered dermal fibroblasts in systemic sclerosis display podoplanin and CD90: B. Nazari, et al.; Am. J. Pathol. 186, 2650 (2016), Abstract — Full Text
- Expression of programmed cell death 1 ligands (PD-L1 and PD-L2) in histiocytic and dendritic cell disorders: J. Xu, et al.; Am. J. Surg. Pathol. 40, 443 (2016), Abstract
- Clonorchis sinensis omega-class glutathione transferases play major roles in the protection of the reproductive system during maturation and the response to oxidative stress: J.G. Kim, et al.; Parasit. Vectors 9, 337 (2016), Application(s): IHC using formaldehyde-fixed embedded adult worm sections, Abstract — Full Text
- Smooth muscle Hgs deficiency leads to impaired esophageal motility: J. Chen, et al.; Int. J. Biol. Sci. 11, 794 (2015), Abstract — Full Text
- Young investigator challenge: Application of cytologic techniques to circulating tumor cell specimens: Detecting activation of the oncogenic transcription factor STAT3: A.C. Lowe, et al.; Cancer Cytopathol. 123, 696 (2015), Abstract
- Expression of programmed cell death 1 ligand 2 (PD-L2) is a distinguishing feature of primary mediastinal (thymic) large B-cell lymphoma and associated with PDCD1LG2 copy gain: M. Shi, et al.; Am. J. Surg. Pathol. 38, 1715 (2014), Abstract
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