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HDAC substrate (fluorogenic)

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A fluorogenic substrate for histone deacetylase (HDAC). Ex(max): 390nm; Em(max): 460nm.

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Alternative Name	Boc-Lys(Ac)-AMC, MAL, Histone deacetylase substrate (fluorogenic), N-(4-Methyl-7-aminocoumarinyl)-Nα-(t-butoxycarbonyl)-Nω-acetyllysineamide
Appearance	White crystalline solid
CAS	233691-67-3
Formula	C₂₃H₃₁N₃O₆
MW	445.5
Purity	≥99%
Sequence	Boc-Lys(Ac)-AMC (AMC=7-Amino-4-methylcoumarin)
Solubility	Soluble in DMSO and 100% ethanol (1mg/ml)

Use/Stability	As indicated on product label or CoA when stored as recommended.
Handling	Protect from light.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

The Contribution of Romidepsin to the Herbicidal Activity of Burkholderia rinojensis Biopesticide: D.K. Owens, et al.; J. Nat. Prod. 83, 843 (2020), Abstract
Histone deacetylase activity assay: Peng, L., Yuan, Z., et al.; Methods Mol. Biol. 1288, 95 (2015), Abstract
A non-isotopic assay for histone deacetylase activity: K. Hoffmann, et al.; Nucl. Acids Res. 27, 2057 (1999), Abstract

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