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H-Ras (wild-type) (human), (recombinant)

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Substrate for farnesyltransferase (>25%) with Km~4 µM using rat brain FT. Possesses GDP binding at >1:4 GDP/H-ras.

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Formulation	Liquid. In 20mM TRIS-HCl, pH 8.0, containing 45mM sodium chloride, 1mM DTT, 5mM magnesium chloride and 50% glycerol.
MW	28 kDa
Purity	≥95% (SDS-PAGE)
Purity Detail	Purified by multi-step chromatography.
Source	Produced in E. coli.
UniProt ID	P01112

Long Term Storage	-80°C
Shipping	Dry Ice

Regulatory Status	RUO – Research Use Only

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2: Kovalski, J. R., Bhaduri, A., et al.; Mol. Cell 73, 830 (2019), Abstract
Multivalent Small-Molecule Pan-RAS Inhibitors: M.E. Welsch, et al.; Cell 168, 878 (2017), Abstract — Full Text

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