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This antibody is covered by our Worry-Free Guarantee.
Product Details
Alternative Name |
sGCα1β1 |
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Application |
WB |
Application Notes |
Western Blot: Works on endogenous |
Crossreactivity |
Does not cross-react with human and mouse sGCα1. |
Formulation |
Liquid. In 10mM TRIS-HCl, pH 7.5, containing 150mM sodium chloride and 0.02% thimerosal. |
Host |
Chicken |
Immunogen |
Purified rat lung soluble guanylyl cyclase α1β1 (sGCα1β1) (native protein). |
Purity Detail |
Purified IgY from egg yolk. |
Recommendation Dilutions/Conditions |
Western Blot(1:500)Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application. |
Species Reactivity |
Human, Mouse, Rat |
Specificity |
Recognizes endogenous rat sGCα1β1. Recognizes human and mouse sGCβ1. |
UniProt ID |
P19686 |
Worry-free Guarantee |
This antibody is covered by our Worry-Free Guarantee. |
Handling & Storage
Short Term Storage |
+4°C |
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Long Term Storage |
-20°C |
Shipping |
Blue Ice |
Regulatory Status |
RUO – Research Use Only |
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- Down-regulation of soluble guanylyl cyclase expression by cyclic AMP is mediated by mRNA-stabilizing protein HuR: S. Kloss, et al.; Mol. Pharmacol. 65, 1440 (2004), Abstract — Full Text
- Post-transcriptional regulation of soluble guanylyl cyclase expression in rat aorta: S. Kloss, et al.; J. Biol. Chem. 278, 2377 (2003), Abstract — Full Text
- Tissue distribution of the human soluble guanylate cyclases: J. Budworth, et al.; BBRC 263, 6967 (1999), Abstract
- Human soluble guanylate cyclase: functional expression and revised isoenzyme family: U. Zabel, et al.; Biochem. J. 335, 51 (1998), Abstract
- Functional domains of soluble guanylyl cyclase: B. Wedel, et al.; J. Biol. Chem. 270, 24871 (1995), Abstract — Full Text
- Electron paramagnetic resonance spectral evidence for the formation of a pentacoordinate nitrosyl-heme complex on soluble guanylate cyclase: J.R. Stone, et al.; BBRC 207, 572 (1995), Abstract
- Regulation of vascular smooth muscle soluble guanylate cyclase activity, mRNA, and protein levels by cAMP-elevating agents: A. Papapetropoulos, et al.; Hypertension 26, 696 (1995), Abstract — Full Text
- Homologous and heterologous desensitization of a guanylyl cyclase-linked nitric oxide receptor in cultured rat medullary interstitial cells: K. Ujiie, et al.; J. Pharmacol. Exp. Ther. 270, 761 (1994), Abstract
- cAMP regulates soluble guanylate cyclase beta 1-subunit gene expression in RFL-6 rat fetal lung fibroblasts: A. Shimouchi, et al.; Am. J. Physiol. 265, L456 (1993), Abstract
- The nitric oxide and cGMP signal transduction system: regulation and mechanism of action: H.H. Schmidt, et al.; Biochim. Biophys. Acta 1178, 153 (1993), Abstract
Datasheet, Manuals, SDS & CofA
Manuals And Inserts
Certificate of Analysis
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SDS
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