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Guanylin (human)

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Guanylyl cyclase activator

Endogenous intestinal guanylyl cyclase activator.

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Appearance	White lyophilized powder.
CAS	183200-12-6
Formula	C₅₈H₈₇N₁₅O₂₁S₄
MW	1458.7
Purity	≥96%
Sequence	H-Pro-Gly-Thr-Cys-Glu-Ile-Cys-Ala-Tyr-Ala-Ala-Cys-Thr-Gly-Cys-OH (Disulfide bonds between Cys⁴-Cys¹² and Cys⁷-Cys¹⁵).
Solubility	Soluble in water.

Use/Stability	As indicated on product label or CoA when stored as recommended.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Human guanylin: cDNA isolation, structure, and activity: R.C. Wiegand, et al.; FEBS Lett. 311, 150 (1992), Abstract
Guanylin: an endogenous activator of intestinal guanylate cyclase: M.G. Currie, et al.; PNAS 89, 947 (1992), Abstract
Precursor structure, expression, and tissue distribution of human guanylin: F.J. de Sauvage, et al.; PNAS 89, 9089 (1992), Abstract

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