Home Shop Guanosine 5’-O-(3-thiotriphosphate) . tetralithium salt

Guanosine 5’-O-(3-thiotriphosphate) . tetralithium salt

ALX-480-056

Datasheet
Manual
SDS
CofA

Already have an account?

Non-hydrolyzable GTP analog

Used to obtain crystal structures of GTPases and measure their stability in presence of ligands

Guanosine 5’-O-(3-thiotriphosphate) (GTP-g-S) is a non-hydrolyzable analog of guanosine 5’-O-triphosphate (GTP) (Prod. No. ALX-480-057). GTP-g-S stimulates inositol trisphosphate formation in membranes.

Shipping: Available products typically ship within 24/48h, via priority shipping.

Do you need support? Contact Customer Service or Technical Support.

Online Account
Access or Create Your Account

Product Details

Alternative Name	GTP-γ-S . 4Li
Appearance	White to off-white solid.
CAS	94825-44-2
Formula	C₁₀H₁₂N₅O₁₃P₃S . 4Li
MW	535.2 . 27.8
Purity	≥85% (HPLC)
Solubility	Soluble in water (25mg/ml).

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

A functional role for GTP-binding proteins in synaptic vesicle cycling: S.D. Hess, et al.; Science 259, 1169 (1993), Abstract
Guanosine 5′-O-(thiotriphosphate)-dependent inositol trisphosphate formation in membranes is inhibited by phorbol ester and protein kinase C: S. Orellana, et al.; J. Biol. Chem. 262, 1638 (1987), Abstract — Full Text
G proteins: transducers of receptor-generated signals: A.G. Gilman; Ann. Rev. Biochem. 56, 615 (1987), Abstract