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Guanfacine . HCl

BML-AR102

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Adrenergic receptor ligand

Centrally acting α₂-adrenergic receptor agonist. In the guinea pig cerebral cortex, the K_d is 20 and 880 nM for the α_2A– and the α_2C-adrenoceptor, respectively. Antihypertensive agent.

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Product Details

Appearance	White solid.
CAS	29520-14-7 / 29110-48-3
Couple Target	Adrenergic receptor
Couple Type	Ligand
Formula	C₉H₉Cl₂N₃O . HCl
MW	282.5
Purity	≥98% (HPLC)
Solubility	Soluble in water (25 mg/ml).

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended.
Long Term Storage	Ambient
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

From alpha and beta to I1: an overview of sympathetic receptors involved in blood pressure control targets for drug treatment: P. A. van Zweiten, et al.; J. Cardiovasc. Pharmacol. 27, S5 (1996), Abstract
Comparison of the binding activities of some drugs on alpha 2A, alpha 2B and alpha 2C-adrenoceptors and non-adrenergic imidazoline sites in the guinea pig: S. Uhlen, et al.; Pharmacol. Toxicol. 76, 353 (1995), Abstract

Last modified: May 29, 2024

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Guanfacine . HCl

BML-AR102

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

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