AMPIVIEW® RNA probes
Enabling Your Projects 
GMP Services
Bulk Solutions
Research Travel Grant
Have You Published Using an Enzo Product?
Nitric oxide donor
NO donor which spontaneously releases NO under physiological conditions. Half-life of 159 hours under physiological conditions. Selectively inhibits platelet activation and displays cardioprotective effects. Inhibits NF-κB activation. Inhibits endothelial cell proliferation and induces apoptosis in T cells.
Shipping: Available products typically ship within 24/48h, via priority shipping.
Do you need support? Contact Customer Service or Technical Support.
Online Account
Access or Create Your Account
Product Details
| Alternative Name |
S-Nitroso-L-glutathione, N-(N-L-γ-Glutamyl-S-nitroso-L-cysteinyl)-glycine |
|---|---|
| Appearance |
Crystalline solid. |
| CAS |
57564-91-7 |
| Formula |
C10H16N4O7S |
| MW |
336.3 |
| Purity |
≥98% (HPLC) |
| Solubility |
Soluble in water (25mg/ml), DMSO (20mg/ml) or PBS; sparingly soluble in 100% ethanol, methanol or dimethyl formamide. |
Handling & Storage
| Use/Stability |
As indicated on product label or CoA when stored as recommended. |
|---|---|
| Long Term Storage |
-20°C |
| Shipping |
Ambient Temperature |
| Regulatory Status |
RUO – Research Use Only |
|---|
- S-nitrosoglutathione inhibits adipogenesis in 3T3-L1 preadipocytes by S-nitrosation of CCAAT/enhancer-binding protein β: M. Mussbacher, et al.; Sci. Rep. 9, 15403 (2019), Abstract — Full Text
- S-nitrosoglutathione promotes cell wall remodelling, alters the transcriptional profile and induces root hair formation in the hairless root hair defective 6 (rhd6) mutant of Arabidopsis thaliana: C.F. Moro, et al.; New Phytol. 213, 1771 (2017), Abstract
- Chronic p38 mitogen-activated protein kinase inhibition improves vascular function and remodeling in angiotensin II-dependent hypertension: S.A. Potthoff, et al.; J. Renin Angriotensin Aldosterone Syst. 17, 1470320316653280 (2016), Application(s): Assessing vasorelaxation in isolated perfused mouse kidney; renal vasodilator responses, Abstract — Full Text
- ROS-Mediated Inhibition of S-nitrosoglutathione Reductase Contributes to the Activation of Anti-oxidative Mechanisms: I. Kovacs, et al.; Front Plant Sci. 7, 1 (2016), Abstract — Full Text
- Identification of nuclear target proteins for S-nitrosylation in pathogen-treated Arabidopsis thaliana cell cultures: M. Chaki, et al.; Plant Sci. 238, 115 (2015), Application(s): Cell Culture, Abstract
- Action of nitroheterocyclic drugs against Clostridium difficile: Kumar, M., Adhikari, S., et al.; Int. J. Antimicrob. Agents 44, 314 (2014), Abstract
- Polysulfides link H2S to protein thiol oxidation: Greiner, R., Pálinkás, Z., et al.; Antioxid. Redox Signal. 19, 1749 (2013), Abstract
- GSNO attenuates EAE disease by S-nitrosylation-mediated modulation of endothelial-monocyte interactions: R. Prasad, et al.; Glia 55, 65 (2007), Abstract
- Nitric oxide induces SOCS-1 expression in human monocytes in a TNF-alpha-dependent manner: M. C. Gonzalez-Leon, et al.; J. Endotoxin Res. 12, 296 (2006), Abstract
- Modulation of glucose uptake in adipose tissue by nitric oxide-generating compounds: D. McGrowder, et al.; J. Biosci. 31, 347 (2006), Abstract
- Mechanisms of cystic fibrosis transmembrane conductance regulator activation by S-nitrosoglutathione: L. Chen, et al.; J. Biol. Chem. 281, 9190 (2006), Abstract
- S-Nitrosoglutathione reduces inflammation and protects brain against focal cerebral ischemia in a rat model of experimental stroke: M. Khan, et. al.; J. Cereb. Blood Flow Metab. 25, 177 (2005), Abstract
- Association of the ERK1/2 and p38 kinase pathways with nitric oxide-induced apoptosis and cell cycle arrest in colon cancer cells: H. K. Jeon, et al.; Cell. Biol. Toxicol. 21, 115 (2005), Abstract
- Redox regulation of PTEN by S-nitrosothiols: C.X. Yu, et al.; Mol. Pharmacol. 68, 847 (2005), Abstract — Full Text
- Protection from experimental asthma by an endogenous bronchodilator: G. Que, et al.; Science 308, 1618 (2005), Abstract
- Endothelial heme oxygenase-1 induction by hypoxia. Modulation by inducible nitric-oxide synthase and S-nitrosothiols: R. Motterlini, et al.; J. Biol. Chem. 275, 13613 (2000), Abstract — Full Text
- The dual role of S-nitrosoglutathione (GSNO) during thymocyte apoptosis: K. Sandau & B. Brune; Cell Signal. 8, 173 (1996), Abstract
- Nitric oxide inhibits macrophage-colony stimulating factor gene transcription in vascular endothelial cells: H.B. Peng, et al.; J. Biol. Chem. 270, 17050 (1995), Abstract
- Nitric oxide inhibition of endothelial cell mitogenesis and proliferation: R. Sarkar, et al.; Surgery 118, 274 (1995), Abstract
- S-nitrosoglutathione improves functional recovery in the isolated rat heart after cardioplegic ischemic arrest-evidence for a cardioprotective effect of nitric oxide: E.A. Konorev, et al.; J. Pharmacol. Exp. Ther. 274, 200 (1995), Abstract
- Induction and stabilization of I kappa B alpha by nitric oxide mediates inhibition of NF-kappa B: H.B. Peng, et al.; J. Biol. Chem. 270, 14214 (1995), Abstract
- Effects of S-nitroso-glutathione in the human forearm circulation: evidence for selective inhibition of platelet activation: A.J. de Belder, et al.; Cardiovasc. Res. 28, 691 (1994), Abstract
- Biological activity of S-nitrosothiols: the role of nitric oxide: W.R. Mathews & S.W. Kerr; J. Pharmacol. Exp. Ther. 267, 1529 (1993), Abstract
- S-nitroso-glutathione inhibits platelet activation in vitro and in vivo: M.W. Radomski, et al.; Br. J. Pharmacol. 107, 745 (1992), Abstract
- An investigation of some S-nitrosothiols, and of hydroxy-arginine, on the mouse anococcygeus: A. Gibson, et al.; Br. J. Pharmacol. 107, 715 (1992), Abstract
Datasheet, Manuals, SDS & CofA
Manuals And Inserts
Certificate of Analysis
Please enter the lot number as featured on the product label
SDS
Enzo Life Science provides GHS Compliant SDS
If your language is not available please fill out the SDS request form