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Growth and differentiation factor 15 (GDF-15) is a TGF-β family member, made by the placenta and heart tissues, that has a role in regulating inflammatory and apoptotic pathways. GDF-15 has become an immerging marker of early heart disease and has the potential as being used as a molecule for screening patients for early heart failure.
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Figure 1: 1µg in each lane (-) non-reducing conditions and (+) reducing conditions in a 4-20% TRIS-Glycine gel, stained with Coomassie Blue. Human GDF-15 is predicted to be a homodimer with a predicted MW of 24.5 kDa.
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RUO – Research Use Only |
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