Granzyme K (human), (recombinant)

• High Specific Activity: Granzyme K is provided with a defined specific activity, ensuring consistent and reliable enzymatic performance, with detailed activity data available in the lot-specific Certificate of Analysis (CoA).
• Native Source and Activity: Recombinant human granzyme K produced in E. coli, preserving native enzymatic function for accurate biological studies.
• Broad Assay Compatibility: Optimized to hydrolyze Z-Lys-SBzl in a range of standard assay conditions, facilitating diverse experimental applications.
• Exceptional Purity: Purity level of ≥98% (SDS-PAGE), ensuring minimal interference from contaminants in sensitive applications.

Granzyme K is a trypsin-like serine protease located in the granules of natural killer (NK) cells and cytotoxic T lymphocytes (CTLs). It plays a crucial role in inducing apoptosis and also contributes to extracellular processes, such as activating endothelial cells and regulating immune responses. Elevated levels of Granzyme K have been associated with a range of diseases, including viral and bacterial infections.