PKC inhibitor. Has been shown to selectively inhibit several PKC isoenzymes (IC50 = 7nM for PKCα and PKCβ; 6nM for PKCγ; 10nM for PKCδ; 60nM for PKCζ). The compound does not effectively inhibit PKCµ (IC50=20 µM) and therefore can be used to differentiate PKCµ from other isoforms.
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Regulatory Status |
RUO – Research Use Only |
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