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Granulocyte-macrophage colony-stimulating factor (GM-CSF) is hematopoietic growth factor produced by endothelial cells, monocytes, fibroblasts, and T cells. GM-CSF stimulates the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells. GM-CSF promotes immune system development and regulates neutrophil function during infection.
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Figure 1: Serial dilutions of Human GM-CSF (starting at 25 ng/mL) were added to TF1 cells. After 66 hours, cell proliferation was measured and the linear portion of the curve can be used to calculate the ED50.
| Regulatory Status |
RUO – Research Use Only |
|---|
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| Alternative Name | Granulocyte-macrophage colony stimulating factor, CSF-2, Pluripoietin-α, MGI1GM |
|---|---|
| Purity | ≥95% (SDS-PAGE) |
| Source | Produced in E. coli. Contains 125 amino acids. |