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Glutathione peroxidase activity kit

ADI-900-158

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Validated in a variety of sample types
Fast, accurate assay results in less than 30 minutes
Convenient 96 well plate format for higher throughput.

The Glutathione Peroxidase activity kit is a convenient 96-well plate based assay for the higher throughput analysis of glutathione peroxidase activity in a variety of sample matrices in just 30 minutes.

Glutathione, a major intracellular non-protein thiol, protects against free radical damage by providing reducing equivalents for several key antioxidant enzymes. In addition, glutathione acts as a scavenger of hydroxyl radicals and nascent oxygen. Elevated glutathione levels are associated with a reduced rate of illness, higher levels of self-rated health, lower cholesterol, lower body mass index, and lower blood pressure among the elderly. Glutathione provides a primary defense system for the removal of oxidants in the brain. Studies have revealed a correlation between low glutathione levels and damage to neurons that manufacture dopamine, suggesting a link to Parkinson’s disease.

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Product Details

Alternative Name	GPx
Application	Activity assay, Colorimetric detection
Application Notes	For the measurement of glutathione peroxidase in cell lysates, plasma, and tissue from any species.
Contents	Microtiter plate, Assay buffer concentrate, Reaction mix, Glutathione reductase, GSSG

Handling & Storage

Long Term Storage	-20°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

Fungicide-tolerant persister formation during cryptococcal pulmonary infection: W. Xe, et al.; Cell Host Microbe 32, 276 (2024), Abstract
Antioxidant, Anti-Apoptotic, and Anti-Inflammatory Effects of Farrerol in a Mouse Model of Obstructive Uropathy: J.Y. Kim, et al.; Curr. Issues Mol. Biol. 45, 337 (2023), Abstract
Reduction of NrF2 as coadjuvant during the development of persistent periapical lesions: Guerrero-Bobadilla, C., Yáñez-Sánchez, I., et al.; Med. Oral Patol. Oral Cir. Bucal 28, e404 (2023), Abstract
Hydralazine Revives Cellular and Ocular Lens Health-Span by Ameliorating the Aging and Oxidative-Dependent Loss of the Nrf2-Activated Cellular Stress Response: Chhunchha, B., Kubo, E., et al.; Antioxidants (Basel) 12, (2023), Abstract
Evaluation of the Antioxidant Activity of Levetiracetam in a Temporal Lobe Epilepsy Model: I.I. Mejía, et al.; Biomedicines 11, 848 (2023), Abstract
Antioxidant, Antiapoptotic, and Anti-Inflammatory Effects of Hesperetin in a Mouse Model of Lipopolysaccharide-Induced Acute Kidney Injury: A.Y. Yang, et al.; Molecules 28, 2759 (2023), Abstract
Hispidulin Ameliorates Endotoxin-Induced Acute Kidney Injury in Mice: K. Kim, et al.; Molecules 27, 2019 (2022), Abstract
c-Abl tyrosine kinase inhibition attenuate oxidative stress-induced pancreatic β-Cell dysfunction via glutathione antioxidant system: U. Karunakaran, et al.; Transl. Res. 249, 74 (2022), Abstract
Ferredoxin:NADP(H) Oxidoreductase Abundance and Location Influences Redox Poise and Stress Tolerance: M. Kozuleva, et al.; Plant Physiol. 172, 1480 (2022), Abstract
Esophageal Cancer Stem-like Cells Resist Ferroptosis-Induced Cell Death by Active Hsp27-GPX4 Pathway: C.C. Liu, et al.; Biomolecules 12, 48 (2022), Abstract

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Glutathione peroxidase activity kit

ADI-900-158

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Certificate of Analysis

SDS

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