Glutamine Assay

Glutamine, a non-essential amino acid, plays several important metabolic roles. Glutamine demand often outstrips production capacity and must be supplied by the diet. While important for protein synthesis, other roles are equally important. Glutamine is readily converted to glucose, particularly when intense physical activity or other stress increases glucose demand. Glutamine is both a source of nitrogen for synthesis of other molecular classes such as nucleotides and as the primary pathway for ammonia detoxification where it is used by the liver to produce urea allowing for excretion of excess amine/ammonia. Glutamine is essential for immune cells, particularly lymphocytes and macrophages, bolstering the immune response. Finally, glutamine is important to the gastrointestinal tract, providing the primary source of energy for the rapidly dividing cells of the intestinal lining. AkrivisBio’s Glutamine Assay provides a simple sensitive means of quantifying glutamine from a variety of biological samples with a sensitivity in the low nanomole range.