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Gilvocarcin M

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Antitumor antibiotic

Antibiotic. Has antibacterial, antifungal, antiviral and antitumor activities. Interacts with DNA. Less active than gilvocarcin V.

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Alternative Name	Anandimycin B, Toromycin B, Antibiotic 1072A
Appearance	Yellow solid.
CAS	77879-89-1
Formula	C₂₆H₂₆O₉
MW	482.5
Purity	≥95% (HPLC)
RTECS	DI2250000
Solubility	Soluble in dimethyl formamide or DMSO; slightly soluble in methanol or 100% ethanol.
Source	Isolated from Streptomyces sp. MST-AS5353.

Use/Stability	As indicated on product label or CoA when stored as recommended.
Handling	Protect from light.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Photophysical properties of gilvocarcins V and M and their binding constant to calf thymus DNA: R. Oyola, et al.; Photochem. Photobiol. 65, 802 (1997), Abstract
Activation of antitumor agent gilvocarcins by visible light: R.K. Elespuru and S.K. Gonda; Science 223, 69 (1984), Abstract
Gilvocarcins, new antitumor antibiotics. 1. Taxonomy, fermentation, isolation and biological activities: H. Nakano, et al.; J. Antibiot. (Tokyo) 34, 266 (1981), Abstract

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