Genistin

ALX-350-247

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TdT inhibitor

Glucoside of genistein (Prod. No. ALX-350-006) found in soy beans. Useful as a negative control for genistein and other tyrosine kinase inhibitors. Selective inhibitor of terminal deoxyribonucleotidyltransferase (TdT). Displays antioxidant and anticarcinogenic properties.

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Product Details

Alternative Name	Genistein-7-O-glucoside
Appearance	Off-white to light yellow powder.
CAS	529-59-9
Couple Target	TdT
Couple Type	Inhibitor
Formula	C₂₁H₂₀O₁₀
MI	14: 4391
MW	432.4
Purity	≥98% (HPLC, TLC)
RTECS	DJ3093000
Solubility	Soluble in DMSO or dilute aqueous base; insoluble in water.

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Magnetic colloidal nanoformulations to remotely trigger mechanotransduction for osteogenic differentiation: M. Estévez, et al.; J. Colloid Interface Sci. 15, 664 (2024), Abstract
Pro-apoptotic effect and cytotoxicity of genistein and genistin in human ovarian cancer SK-OV-3 cells: E.J. Choi, et al.; Life Sci. 80, 1403 (2007), Abstract
Genistin inhibits UV light-induced plasmid DNA damage and cell growth in human melanoma cells: A. Russo, et al.; J. Nutr. Biochem. 17, 103 (2006), Abstract
Selective inhibitors of terminal deoxyribonucleotidyltransferase (TdT): baicalin and genistin: Y. Uchiyama, et al.; Biochim. Biophys. Acta 1725, 298 (2005), Abstract
Inhibition of CYP1A1 enzyme activity in mouse hepatoma cell culture by soybean isoflavones: H.G. Shertzer, et al.; Chem. Biol. Interact. 123, 31 (1999), Abstract
Daidzein and genistein but not their glucosides are absorbed from the rat stomach: M.K. Piskula, et al.; FEBS Lett. 447, 287 (1999), Abstract
Soybean isoflavones, genistein and genistin, inhibit rat myoblast proliferation, fusion and myotube protein synthesis: S. Ji, et al.; J. Nutr. 129, 1291 (1999), Abstract

Related Products

Genistein (synthetic)

ALX-350-006

Tyrosine kinase inhibitor

26 citations

Alternative Name	4′,5,7-Trihydroxyisoflavone
CAS	446-72-0
Couple Type	Inhibitor
Purity	≥98% (HPLC)

ALX-350-006-M010 — 10 mg

$45.00

Genistein (synthetic) quantity
ALX-350-006-M025 — 25 mg

$75.00

Genistein (synthetic) quantity
ALX-350-006-M050 — 50 mg

$146.00

Genistein (synthetic) quantity
ALX-350-006-M100 — 100 mg

$236.00

Genistein (synthetic) quantity
ALX-350-006-G001 — 1 g

$790.00

Genistein (synthetic) quantity

Last modified: May 29, 2024

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Genistin

ALX-350-247

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