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GEA 5024

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Nitric oxide donor

Water soluble and stable nitric oxide donor.

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Alternative Name	5-Amino-3-(3-chloro-2-methylphenyl)-1,2,3,4-oxatriazolium chloride
Appearance	White to off-white crystalline solid.
CAS	144575-27-9
Formula	C₈H₇ClN₄O . HCl
MW	210.6 . 36.5
Purity	≥97% (HPLC)
Solubility	Soluble in water.

Use/Stability	As indicated on product label or CoA when stored as recommended.
Long Term Storage	+4°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Sodium nitroprusside-induced mitochondrial apoptotic events in insulin-secreting RINm5F cells are associated with MAP kinases activation: J. C. Bernabe, et al.; Exp. Cell. Res. 269, 222 (2004), Abstract
Nitric oxide-mediated apoptosis of K-1735 melanoma cells is associated with downregulation of Bcl-2: K. Xie, et al.; Oncogene 15, 771 (1997), Abstract
Expression of nitric oxide synthase in skeletal muscle: a novel role for nitric oxide as a modulator of insulin action: S. Kapur, et al.; Diabetes 46, 1691 (1997), Abstract
Inhibition by nitric oxide-donors of human polymorphonuclear leucocyte functions: E. Moilanen, et al.; Br. J. Pharmacol. 109, 852 (1993), Abstract

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