Gastrin I (rat), ELISA kit

• Efficient – only 50µl sample volume required
• Ultrasensitive – detect <80 pg/ml
• Higher throughput – assay up to 37 samples in duplicate per 96 well kit

The Gastrin I (rat), EIA kit is a colorimetric competitive enzyme immunoassay kit with results in 5 hours. Absorbance is read at 405 nm. Ready-to-use liquid color-coded reagents are provided to reduce error in the lab. This kit utilizes low sample volume and the ability to measure up to 37 samples in duplicate per 96-well plate.

Gastrins are a family of sequence-related carboxyamidated peptides produced by endocrine G cells of the antrum mucosa, and are potent stimulators of gastric acid secretion. Antral distension, partially digested proteins, amino acids, and vagal stimulation resulting from smelling, tasting, chewing or swallowing food all contribute to gastrin release from G cell storage. In addition, caffeine, alcohol, hypoglycemia, antacids and elevated calcium levels also stimulate gastrin release. Increased serum gastrin levels are associated with duodenal ulcers, Helicobacter pylori infections, colorectal carcinomas, and other tumors and cancerous lesions.