Specific receptor for cholera toxin.
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Product Details
| Alternative Name | 
						 GM1 . Na (bovine brain), Monosialoganglioside GM1 . Na (bovine brain)  | 
				
|---|---|
| Appearance | 
						 Lyophilized.  | 
				
| CAS | 
						 37758-47-7  | 
				
| Couple Target | 
						 Cholera toxin  | 
				
| Couple Type | 
						 Receptor  | 
				
| Formula | 
						 C73H130N3O31 . Na  | 
				
| MI | 
						 14: 4364  | 
				
| MW | 
						 1545.8 . 23.0 (calculated on sphingosine C18:1 and stearic acid)  | 
				
| Purity | 
						 ≥98% (TLC)  | 
				
| Sequence | 
						 [II3Neu5AcGgOse4Cer] [β-Gal-(1→3)-β-GalNAc-(1→4)-[α-Neu5Ac-(2→3)]-β-Gal(1→4)-β-Glc-(1→1′)-Cer]  | 
				
Handling & Storage
| Use/Stability | 
						 As indicated on product label or CoA when stored as recommended.  | 
				
|---|---|
| Long Term Storage | 
						 -20°C  | 
				
| Shipping | 
						 Ambient Temperature  | 
				
| Regulatory Status | 
						 RUO – Research Use Only  | 
				
|---|
- Impaired ganglioside metabolism in Huntington’s disease and neuroprotective role of GM1: V. Maglione, et al.; J. Neurosci. 30, 4072 (2010), Abstract — Full Text
 - Binding of amyloid beta-peptide to ganglioside micelles is dependent on histidine-13: M.P. Williamson, et al.; Biochem. J. 397, 483 (2006), Abstract — Full Text
 - Role of membrane gangliosides in the binding and action of bacterial toxins: P.H. Fishman; J. Membr. Biol. 69, 85 (1982)
 
Related Products
		| Couple Type | Inhibitor | 
|---|---|
| Purity | ≥98% (TLC) | 
		| Alternative Name | Ceramide tetrahexoside, Gangliotetraosylceramide, Asialoganglioside-GM1 | 
|---|---|
| CAS | 71012-19-6 | 
| Purity | Single Spot (TLC) | 
		| Alternative Name | Asialoganglioside-GM2, Ceramide trihexoside, Gangliotriosylceramide | 
|---|---|
| CAS | 35960-33-9 | 
| Purity | ≥98% | 
		| Alternative Name | N-Palmitoyl-D-erythro-sphingosine, N-Hexadecanoyl-D-erythro-sphingosine, N-Palmitoyl ceramide | 
|---|---|
| CAS | 24696-26-2 | 
| Couple Type | Activator | 
| Purity | ≥98% (TLC) | 
Last modified: May 29, 2024
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