Home Shop Gallotannin

Gallotannin

ALX-270-418

Datasheet
Manual
SDS
CofA

Already have an account?

Inhibitor of PARG and eNOS

Inhibitor of poly(ADP-ribose) glycohydrolase (PARG). Cytoprotective in oxidatively stressed cells. Inhibitor of endothelial nitric oxide synthase (eNOS; NOS III) and weak inhibitor of inducible (iNOS; NOS II) and neuronal nitric oxide synthase (nNOS; NOS I). Induces cyclooxygenase-2 (COX-2) expression. Free radical scavenger.

Shipping: Available products typically ship within 24/48h, via priority shipping.

Do you need support? Contact Customer Service or Technical Support.

Online Account
Access or Create Your Account

Product Details

Alternative Name	Tannic acid
Appearance	Beige to light brown powder.
CAS	1401-55-4
Couple Target	NOS, PARG
Couple Type	Inhibitor
Formula	C₇₆H₅₂O₄₆
MI	14: 9052
MW	1701.2
Purity	≥95%
RTECS	WW5075000
Solubility	Soluble in water, 100% ethanol, acetone or warm glycerol.
Source	Occurs in the bark and fruit of many plants, notably in the bark of the oak species, in sumac and myrobalan.

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended.
Handling	Protect from light.
Long Term Storage	+4°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Nicotinamide adenine dinucleotide is transported into mammalian mitochondria: Davila, A., Liu, L., et al.; Elife 7, (2018), Abstract
Specific killing of DNA damage-response deficient cells with inhibitors of poly(ADP-ribose) glycohydrolase: Gravells, P., Grant, E., et al.; DNA Repair (Amst.) 52, 81 (2017), Abstract
Diadenosine 5′, 5′′′-P1,P4-tetraphosphate (Ap4A) is synthesized in response to DNA damage and inhibits the initiation of DNA replication: A.S. Marriott, et al.; DNA Repair (Amst.) 33, 90 (2015), Application(s): Cell Culture, Abstract
Poly(ADP-ribosyl) glycohydrolase prevents the accumulation of unusual replication structures during unperturbed S phase: Ray Chaudhuri, A., Ahuja, A. K., et al.; Mol. Cell. Biol. 35, 856 (2015), Abstract
Inhibition of poly(ADP-ribose) glycohydrolase (PARG) specifically kills BRCA2-deficient tumor cells: Fathers, C., Drayton, R. M., et al.; Cell Cycle 11, 990 (2012), Abstract
The efficacy of protective effects of tannic acid, gallic acid, ellagic acid, and propyl gallate against hydrogen peroxide-induced oxidative stress and DNA damages in IMR-90 cells: C.H. Chen, et al.; Mol. Nutr. Food Res. 51, 962 (2007), Abstract
Prominent free radicals scavenging activity of tannic acid in lead-induced oxidative stress in experimental mice: I.H. El-Sayed, et al.; Toxicol. Ind. Health 22, 157 (2006), Abstract
Tannic acid in plant dust causes airway obstruction: D. Taubert, et al.; Thorax 60, 789 (2005), Abstract
Inhibition of poly(ADP-ribose) glycohydrolase by gallotannin selectively up-regulates expression of proinflammatory genes: E. Rapizzi, et al.; Mol. Pharmacol. 66, 890 (2004), Abstract
The poly(ADP-ribose) glycohydrolase inhibitor gallotannin blocks oxidative astrocyte death: W. Ying, et al.; Neuroreport 11, 1385 (2000), Abstract

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Datasheet

Certificate of Analysis

Please enter the lot number as featured on the product label

Lot No. :

SDS

Enzo Life Science provides GHS Compliant SDS

English (EU) SDS

If your language is not available please fill out the SDS request form

Your Cart

Your Cart

Gallotannin

ALX-270-418

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Certificate of Analysis

SDS

Change Country

Tell us about You

Tell us about your paper

Tell us about You

Tell us about your project