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Fusidic acid . sodium salt

ALX-380-011

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Elongation factor G inhibitor

Antibiotic which suppresses nitric oxide (NO) toxicity in pancreatic islet cells. Inhibits protein synthesis by inhibition of elongation factor G at the level of the ribosome.

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Product Details

Appearance	White to off-white solid.
CAS	751-94-0
Couple Target	Elongation factor
Couple Type	Inhibitor
Formula	C₃₁H₄₇O₆ . Na
MI	14: 4317
MW	515.7 . 23.0
Purity	≥98% (TLC)
Solubility	Soluble in water (50mg/ml).

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended.
Long Term Storage	+4°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Dumb and dumber–the potential waste of a useful antistaphylococcal agent: emerging fusidic acid resistance in Staphylococcus aureus: B.P. Howden & M.L. Grayson; Clin. Infect. Dis. 42, 394 (2006), Review, Abstract
Fusidic acid in vitro activity: P. Collignon and J. Turnidge; Int. J. Antimicrob. Agents 12, S45 (1999), Review, Abstract
Fusidic acid non-antibacterial activity: K. Christiansen; Int J Antimicrob Agents 12, S73 (1999), Review, Abstract
Fusidic acid suppresses nitric oxide toxicity in pancreatic islet cells: V. Burkart, et al.; Biochem. Pharmacol. 48, 1379 (1994), Abstract
Mechanism of protein synthesis inhibition by fusidic acid and related antibiotics: N. Tanaka, et al.; BBRC 30, 278 (1968), Abstract
On the Mode of Action of Fusidic Acid: C.L. Harvey, et al.; Biochemistry 5, 3320 (1966), Abstract
Fusidic acid: a new antibiotic: W.O. Godtfredsen, et al.; Nature 193, 987 (1962), Abstract

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Fusidic acid . sodium salt

ALX-380-011

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Certificate of Analysis

SDS

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