Furoxan

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Releases NO in the presence of thiols

A novel NO donor which only releases NO in the presence of thiols. It is a potent vasodilator and inhibitor of platelet aggregation.

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Alternative Name	4-Phenyl-3-furoxancarbonitrile
Appearance	White solid.
CAS	125520-62-9
Formula	C₉H₅N₃O₂
MW	187.2
MeltingPoint	72-74°C
Purity	≥99% (HPLC)
Solubility	Soluble in ethanol (25 mg/ml) or DMSO (25 mg/ml).

Use/Stability	As indicated on product label or CoA when stored as recommended. Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

A new class of furoxan derivatives as NO donors: mechanism of action and biological activity: R. Ferioli, et al.; Br. J. Pharmacol. 114, 816 (1995), Abstract — Full Text
Furoxans as nitric oxide donors. 4-Phenyl-3-furoxancarbonitrile: thiol-mediated nitric oxide release and biological evaluation: C. Medana, et al.; J. Med. Chem. 37, 4412 (1994), Abstract

Last modified: May 29, 2024

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