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Fostriecin

ALX-380-065

15 citations

  • ALX-380-065-C010   —   10 µg
    $236.00

Antitumor antibiotic. Catalytic inhibitor of topoisomerase II. Strong protein phosphatase 2A (PP2A) inhibitor (IC50=3.2nM). Weak inhibitor for PP1 (IC50=131µM). No apparent effect on PP2B. The binding site for fostriecin on PP2A is different from that of okadaic acid (see Prod. No. ALX-350-003).

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Regulatory Status

RUO – Research Use Only