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Fluvastatin . sodium salt

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Anticholesterol agent. HMG-CoA inhibitor.

Anticholesterol agent. HMG-CoA reductase inhibitor and antioxidant.

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Appearance	Off-white to light yellow solid.
CAS	93957-55-2
Couple Target	HMG-CoA
Couple Type	Inhibitor
Formula	C₂₄H₂₅FNO₄ . Na
MI	14: 4218
MW	410.5 . 23.0
Purity	≥98% (HPLC)
RTECS	MJ9675050
Solubility	Soluble in water.
Source	Synthetic.

Use/Stability	As indicated on product label or CoA when stored as recommended. Stock solutions are stable for up to 6 months when stored at -20°C.
Handling	Protect from light.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Pitavastatin Is a Highly Potent Inhibitor of T-Cell Proliferation: L. Voss, et al.; Pharmaceuticals (Basel) 14, 727 (2021), Abstract
MyoScreen, a High-Throughput Phenotypic Screening Platform Enabling Muscle Drug Discovery: Young, J., Margaron, Y., et al.; SLAS Discov. 23, 790 (2018), Abstract
Novel synthetic inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase activity that inhibit tumor cell proliferation and are structurally unrelated to existing statins: Perchellet, J. P., Perchellet, E. M., et al.; Int. J. Mol. Med. 24, 633 (2009), Abstract
Breast cancer growth prevention by statins: Campbell, M. J., Esserman, L. J., et al.; Cancer Res. 66, 8707 (2006), Abstract
Effect of fluvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, on nitric oxide-induced hydroxyl radical generation in the rat heart: T. Obata, et al.; Biochim. Biophys. Acta 1536, 55 (2001), Abstract
Antioxidative effect of fluvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, on peroxidation of phospholipid liposomes: A. Yamamoto, et al.; J. Pharm. Pharmacol. 53, 227 (2001), Abstract
Folate and carcinogenesis: an integrated scheme: S.W. Choi and J.B. Mason; J. Nutr. 130, 129 (2000), Abstract — Full Text

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