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FlexISH® IGK/IGL DistinguISH™ Probe

ZTV-Z-2295

Axxora Marketplace
  • ZTV-Z-2295-50   —   50 µl
    $559.00

The FlexISH® IGK/IGL DistinguISH™ Probe is designed to detect rearrangements affecting the chromosomal region 2p11.2 and 22q11.22 harboring the IGK and IGL gene cluster region, respectively. Translocations involving the immunoglobulin genes are recurring events of B-cell oncogenesis. In all of these translocations, an oncogene is activated and overexpressed by juxtaposition to IG regulatory sequences. Burkitt lymphoma is characterized by reciprocal translocations involving the MYC gene and one of the IG loci.

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Regulatory Status

RUO – Research Use Only