Fibroblast activation protein (human) monoclonal antibody (F11-24)

FAP

Flow Cytometry, IHC (FS), IP

Not suitable for Immunohistochemistry (paraffin sections).

F11-24

Cross-reacts with a subset of endocrine cells in the pancreatic islets, presumably glucagon-producing A cells.

Liquid. In PBS.

Mouse

Human FAP (fibroblast activation protein).

IgG1

Protein A-affinity purified.

Immunohistochemistry (suitable for stainings on unfixed, acetone-fixed or ethanol-fixed frozen sections; acetone-fixed frozen sections showed optimal staining results)Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application.

Human

FAP is a cell surface glycoprotein of reactive human fibroblasts. Among the normal adult organs tested, MAb to FAP does not show immunoreactivity in immunohistological studies with either resting fibroblasts (fibrocytes) of the normal organ mesenchyme or the parenchymal cells. The single exception noted is a subset of endocrine cells in the pancreatic islets, presumably glucagon-producing A cells.

Q12884

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