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Factor XIII (V34L mutant) (A Subunit) (human) (recombinant)

NZY-T063

  • NZY-T063-200   —   200 µg
    $520.00

Recombinant human Factor XIII-Val34Leu is a homodimer (a2) composed of two chains held together by non covalent bonds. After activation of the zymogen by Thrombin and Ca2+ to its active form (a*2, Factor XIIIa), Factor XIIIa-Val34Leu catalyzes the formation of covalent bridges (ε-(γ-glutamyl)lysine bonds) between fibrin units to increase the elasticity of the clot network. The resulting cross-linked fibrin is insoluble and resistant to lysis. At position 34 Valine has been replaced by Leucine. Please note that numerotation corresponds to the wild type protein without hexahistidine-tag.

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Regulatory Status

RUO – Research Use Only