Factor XIII (A Subunit) (rat) (recombinant) (His)
NZY-T065
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Recombinant rat Factor XIII is a homodimer (a2) composed of two chains held together by non covalent bonds. After activation of the zymogen by Thrombin and Ca2+ to its active form (a*2, Factor XIIIa), Factor XIIIa catalyzes the formation of covalent bridges (ε-(γ-glutamyl)lysine bonds) between fibrin units to increase the elasticity of the clot network. The resulting crosslinked fibrin is insoluble and resistant to lysis.
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Regulatory Status |
RUO – Research Use Only |
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