Home Shop Estrogen receptor α monoclonal antibody (C-542)

Estrogen receptor α monoclonal antibody (C-542)

ENZ-ABS689

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The Estrogen receptors (ER), mainly ERalpha and ERbeta, are members of the nuclear steroid hormone receptor family and are composed of three domains, an N-terminal domain required for maximal transactivation function (TAF), a DNA binding domain, and a steroid binding domain. Estrogen has pleiotropic effects on the growth, development, and maintenance of diverse tissues.

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Product Details

Alternative Name	ESR
Application	ICC, IHC, IP, WB
Application Notes	Detects a band of 66.3 kDa by Western blot.
Clone	C-542
Formulation	Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
GenBank ID	M12674
Host	Mouse
Immunogen	Synthetic peptide corresponding to the sequence near the C-terminus of human Estrogen Receptor α.
Isotype	IgG1
Purity Detail	Protein G affinity purified.
Recommendation Dilutions/Conditions	Western Blot (1:500, colorimetric)Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application.
Source	Purified from hybridoma tissue culture supernatant.
Species Reactivity	Hamster, Human, Mouse, Rat
UniProt ID	P03372
Worry-free Guarantee	This antibody is covered by our Worry-Free Guarantee.