Home Shop ERp57 monoclonal antibody (MaP.Erp57)

ERp57 monoclonal antibody (MaP.Erp57)

ADI-SPA-725

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ERp57 (also known as Grp58), a member of the Thioredoxin superfamily, is an ER protein with disulfide isomerase activity. It has been shown to increase after oncogenic transformation and to be a component of the MHC Class I peptide-loading complex.

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This antibody is covered by our Worry-Free Guarantee.

ERp57 monoclonal antibody (MaP.Erp57) Western blot — Western blot analysis of ERp57, mAb (MaP.Erp57) (Prod. no. ADI-SPA-725) : Lane 1: HeLa Cell Lysate, Lane 2: HeLa Cell Lysate (Heat Shocked), Lane 3: MDCK, Lane 4: MDCK (Heat Shocked), Lane 5: CHO-K1, Lane 6: ESK-4, Lane 7: Vero.

Product Details

Alternative Name	PDIA3, ERp60, ERp61, GRP57, Grp58
Application	IHC, WB
Application Notes	Detects a band of ~58kDa by Western blot.
Clone	MaP.Erp57
Formulation	Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
GenBank ID	U42068
Host	Mouse
Immunogen	Recombinant human ERp57.
Isotype	IgG1
Purity Detail	Protein G affinity purified.
Recommendation Dilutions/Conditions	Western Blot (1:1,000, ECL)Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application.
Source	Purified from ascites.
Species Reactivity	Dog, Hamster, Human, Monkey, Porcine
UniProt ID	P30101
Worry-free Guarantee	This antibody is covered by our Worry-Free Guarantee.

Handling & Storage

Handling	Avoid freeze/thaw cycles.
Long Term Storage	-20°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

Single-cell analysis of senescent epithelia reveals targetable mechanisms promoting fibrosis: O’Sullivan, E. D., Mylonas, K. J., et al.; JCI Insight 7, (2022), Application(s): WB, Abstract
Endoplasmic reticulum stress and unfolded protein response profile in quadriceps of sarcopenic patients with respiratory diseases: Barreiro, E., Salazar-Degracia, A., et al.; J. Cell. Physiol. 234, 11315 (2019), Abstract
Early-onset torsion dystonia: a novel high-throughput yeast genetic screen for factors modifying protein levels of torsinAΔE: L.F. Zacchi, et al.; Dis. Model. Mech. 10, 1129 (2017), Application(s): WB, Abstract — Full Text
Effect of doxycycline-regulated ERp57 expression on specific thrombopoietin productivity of recombinant CHO cells: G.M. Lee, et al.; Biotechnol. Prog. 19, 179 (2003), Application(s): WB using human samples, Abstract
Recruitment of MHC class I molecules by tapasin into the transporter associated with antigen processing-associated complex is essential for optimal peptide loading: F. Momburg, et al.; J. Immunol. 168, 1950 (2002), Application(s): WB using human samples, Abstract
Proteomic analysis of lung adenocarcinoma: identification of a highly expressed set of proteins in tumors: D.G. Beer, et al.; Clin. Cancer Res. 8, 2298 (2002), Application(s): IHC, WB using human samples, Abstract

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ERp57 monoclonal antibody (MaP.Erp57)

ADI-SPA-725

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Handling & Storage

Datasheet, Manuals, SDS & CofA

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ERp57 monoclonal antibody (MaP.Erp57)

ADI-SPA-725

Product Details

Handling & Storage

Related Products

HeLa (heat shocked) , (cell lysate)

ADI-LYC-HL101

Goat anti-mouse IgG F(ab’)2, polyclonal antibody (HRP conjugate)

ADI-SAB-100

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Certificate of Analysis

SDS

Goat anti-mouse IgG F(ab’)₂, polyclonal antibody (HRP conjugate)