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Enhancer for Ligands

ALX-804-034

19 citations

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Enhances biological activity of TRAIL, soluble (human) (recombinant) and FasL, soluble (human) (recombinant).

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This antibody is covered by our Worry-Free Guarantee.

Product Details

Formulation	Liquid. In PBS, pH 7.4, containing 50% glycerol. Contains no preservatives.
Worry-free Guarantee	This antibody is covered by our Worry-Free Guarantee.

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended.
Handling	Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Short Term Storage	+4°C
Long Term Storage	-20°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

Mitochondrial reactive oxygen is critical for IL-12/IL-18-induced IFN-γ production by CD4+ T cells and is regulated by Fas/FasL signaling: G. Rackov, et al.; Cell Death Dis. 13, 531 (2022), Abstract
RIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation: G. Liccardi, et al.; Mol. Cell 73, 413 (2019), Abstract — Full Text
Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2: A. Annibaldi, et al.; Mol. Cell 69, 566 (2018), Abstract — Full Text
Artesunate shows potent anti-tumor activity in B-cell lymphoma: T. K. Vatsveen, et al.; J. Hematol. Oncol. 11, 23 (2018), Abstract — Full Text
MK2 Phosphorylates RIPK1 to Prevent TNF-Induced Cell Death: I. Jaco, et al.; Mol. Cell 66, 698 (2017), Reactant(s) Mouse, Abstract — Full Text
Id3 Controls Cell Death of 2B4+ Virus-Specific CD8+ T Cells in Chronic Viral Infection: A.J. Menner, et al.; J. Immunol. 195, 2103 (2015), Abstract
Soluble CD40 ligand contributes to dendritic cell-mediated T-cell dysfunction in HIV-1 infection: E.A. Miller, et al.; AIDS 29, 1287 (2015), Application(s): WB / Reactant(s) Human, Abstract — Full Text
Identification and characterization of agonist epitopes of the MUC1-C oncoprotein: C. Jochems, et al.; Cancer Immunol. Immunother. 63, 161 (2014), Application(s): Stimulation of dendritic cells, Abstract
Resistance to TRAIL in non-transformed cells is due to multiple redundant pathways.: van Dijk, M., Samali, A., et al.; Cell Death Dis. 4, e702 (2013), Reactant(s): Human, Abstract
Immunological targeting of tumor cells undergoing an epithelial-mesenchymal transition via a recombinant brachyury-yeast vaccine: D.H. Hamilton, et al.; Oncotarget 4, 1777 (2013), Application(s): Stimulation of dendritic cells, Abstract — Full Text