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EC SOD polyclonal antibody

ADI-SOD-106

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SOD (Superoxide dismutase) is responsible for the elimination of cytotoxic active oxygen by catalyzing the dismutation of the superoxide radical to oxygen and hydrogen peroxide. There are three SOD isoenzymes in mammalian cells, they are: EC SOD (extracellular SOD), Cu/Zn SOD (copper and zinc-containing SOD) and Mn SOD (manganese-containing SOD).

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This antibody is covered by our Worry-Free Guarantee.

EC SOD polyclonal antibody Western blot — Western blot analysis of EC SOD: Lane 1: MW Marker, Lane 2: Rat Lung Tissue Extract, Lane 3: Mouse Lung Tissue Extract, Lane 4: Human EC SOD Protein.

Product Details

Alternative Name	Superoxide Dismutase, SOD3
Application	WB
Application Notes	Detects a band of ~35-40kDa (glycosylation dependent) by Western blot.
Formulation	Liquid. In PBS containing 50% glycerol and 0.09% sodium azide.
Host	Rabbit
Immunogen	Synthetic peptide corresponding to a portion of EC SOD. The sequence is completely conserved in human, mouse, rat and rabbit.
Purity Detail	Protein A affinity purified.
Recommendation Dilutions/Conditions	Western Blot (1:1,000, ECL)Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application.
Source	Purified from rabbit serum.
Species Reactivity	Human, Mouse, Rat
UniProt ID	P08294
Worry-free Guarantee	This antibody is covered by our Worry-Free Guarantee.

Handling & Storage

Handling	Avoid freeze/thaw cycles.
Long Term Storage	-20°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

Potential Role of Superoxide Dismutase 3 (SOD3) in Resistance to Influenza A Virus Infection: F. Chen, et al.; Antioxidants 12, 354 (2023), Abstract
Cerebrovascular endothelial dysfunction induced by mercury exposure at low concentrations: G.A. Wiggers, et al.; Neurotoxicology 53, 282 (2016), Application(s): Western blot, Abstract
MAPK pathway activation by chronic lead-exposure increases vascular reactivity through oxidative stress/cyclooxygenase-2-dependent pathways: M.R. Simões, et al.; Toxicol. Appl. Pharmacol. 283, 127 (2015), Application(s): Western Blotting, Abstract
Extracellular Superoxide Dismutase Protects against Proteinuric Kidney Disease: R.J. Tan, et al.; J. Am. Soc. Nephrol. 26, 2447 (2015), Application(s): IHC on FFPE human kidney sections, Abstract — Full Text
Hydrocortisone normalizes phosphodiesterase-5 activity in pulmonary artery smooth muscle cells from lambs with persistent pulmonary hypertension of the newborn: M. Perez, et al.; Pulm. Circ. 4, 71 (2014), Application(s): WB using fetal lamb pulmonary arterial smooth muscle cell (FPASMC) lysates, Abstract — Full Text
Activation of PPARδ prevents endothelial dysfunction induced by overexpression of amyloid-β precursor protein: L.V. d’Uscio, et al.; Cardiovasc. Res. 96, 504 (2012), Application(s): Western Blot of mouse aorta lysates, Abstract — Full Text
Low mercury concentrations cause oxidative stress and endothelial dysfunction in conductance and resistance arteries: M. Salaices, et al.; Am. J. Physiol. Heart Circ. Physiol. 295, H1033 (2008), Application(s): WB using rat tissue, Abstract

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Last modified: May 29, 2024

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EC SOD polyclonal antibody

ADI-SOD-106

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Datasheet, Manuals, SDS & CofA

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