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Ebelactone A

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Esterase inhibitor

Inhibitor of esterases, lipases and N-formylmethionine aminopeptidase.

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Alternative Name	3,11-Dihydroxy-2,4,6,8,10,12-hexamethyl-9-oxo-6-tetradecenoic 1,3-lactone
Appearance	White crystalline powder.
CAS	76808-16-7
Couple Target	Aminopeptidase, Esterase
Couple Type	Inhibitor
Formula	C₂₀H₃₄O₄
MW	338.5
Purity	≥99%
Solubility	Soluble in methanol.
Source	Microbial.

Use/Stability	As indicated on product label or CoA when stored as recommended.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Acylpeptide hydrolase is a novel regulator of KRAS plasma membrane localization and function: Tan, L., Cho, K. J., et al.; J. Cell Sci. 132, (2019), Abstract
Acylpeptide hydrolase: inhibitors and some active site residues of the human enzyme: A. Scaloni, et al.; J. Biol. Chem. 267, 3811 (1992), Abstract — Full Text
Structural studies on ebelactone A and B, esterase inhibitors produced by actinomycetes: K. Uotani, et al.; J. Antibiot. (Tokyo) 35, 1495 (1982), Abstract
Biosynthetic studies of ebelactone A and B by 13C NMR spectrometry: K. Uotani, et al.; J. Antibiot. (Tokyo) 35, 1670 (1982), Abstract
Ebelactone, an inhibitor of esterase, produced by actinomycetes: H. Umezawa, et al.; J. Antibiot. (Tokyo) 33, 1594 (1980), Abstract

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