Home Shop Dnmt1 monoclonal antibody (60B1220.1)

Dnmt1 monoclonal antibody (60B1220.1)

ALX-804-369

20 citations

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Dnmt1 monoclonal antibody (60B1220.1) Immunohistochemistry

Product Details

Alternative Name	DNA methyltransferase-1
Application	ChIP, ICC, IHC (PS), IP, WB
Clone	60B1220.1
Formulation	Liquid. In PBS containing 0.05% BSA and 0.05% sodium azide.
Host	Mouse
Immunogen	Synthetic peptide corresponding to aa 637-650 of human Dnmt1 (DNA methyltransferase-1).
Isotype	IgG1
Purity Detail	Protein G-affinity purified.
Recommendation Dilutions/Conditions	Immunohistochemistry (paraffin sections, 1-2µg/ml)Western Blot (0.1-0.5µg/ml)Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application.
Species Reactivity	Human, Mouse, Zebrafish
Technical Info / Product Notes	Replacement for ADI-KAM-TF040
UniProt ID	P26358
Worry-free Guarantee	This antibody is covered by our Worry-Free Guarantee.

Handling & Storage

Use/Stability	Stable for 6 months when stored at +4°C.
Handling	Avoid freeze/thaw cycles.
Short Term Storage	+4°C
Long Term Storage	-20°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

Stromal induction of BRD4 phosphorylation Results in Chromatin Remodeling and BET inhibitor Resistance in Colorectal Cancer.: Yu, Q., Lee, P. L., et al.; Nat. Commun. 12, 4441 (2021), Application(s): WB, Abstract
Interaction of the epigenetic integrator UHRF1 with the MYST domain of TIP60 inside the cell: W. Ashraf, et al.; J. Exp. Clin. Cancer Res. 36, 188 (2017), Abstract — Full Text
Mitochondrial DNMT3A and DNA methylation in skeletal muscle and CNS of transgenic mouse models of ALS: Wong, M., Gertz, B., et al.; Front. Cell. Neurosci. 7, 279 (2014), Abstract
Immunology of cutaneous vasculitis associated with both etanercept and infliximab: M.D. Srivastava, et al.; Scand. J. Immunol. 61, 329 (2005), Abstract
Establishment and characterization of SRIK-NKL: a novel CD8+ natural killer/T cell line derived from a patient with leukemic phase of acute lymphoblastic lymphoma: B.I. Srivastava and M.D. Srivastava; Leuk. Res. 29, 771 (2005), Abstract
5-Aza-deoxycytidine induces selective degradation of DNA methyltransferase 1 by a proteasomal pathway that requires the KEN box, bromo-adjacent homology domain, and nuclear localization signal: K. Ghoshal, et al.; Mol. Cell. Biol. 25, 4727 (2005), Abstract
Deregulation of DNA methyltransferases and loss of parental methylation at the insulin-like growth factor II (Igf2)/H19 loci in p53 knockout mice prior to tumor development: I.Y. Park, et al.; J. Cell Biochem. 94, 585 (2005), Abstract
An association of DNMT3b protein expression with P16INK4a promoter hypermethylation in non-smoking female lung cancer with human papillomavirus infection: T.S. Lin, et al.; Cancer Lett. 226, 77 (2005), Abstract
Induction of DNA methylation and gene silencing by short interfering RNAs in human cells: H. Kawasaki and K. Taira; Nature 431, 211 (2004), Abstract
Components of a pathway maintaining histone modification and heterochromatin protein 1 binding at the pericentric heterochromatin in Mammalian cells: H. Xin, et al.; J. Biol. Chem. 279, 9539 (2004), Abstract — Full Text

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Dnmt1 monoclonal antibody (60B1220.1)

ALX-804-369

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

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