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Dimethyl-bisphenol A

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HIF-1α inhibitor

A HIF-1α degradation promotor.

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Appearance	White solid.
CAS	1568-83-8
Couple Target	HIF
Couple Type	Inhibitor
Formula	C₁₇H₂₀O₂
MW	256.3
Purity	≥98% (TLC)
Solubility	Soluble in DMSO (>25 mg/ml) or ethanol (>25 mg/ml)
Source	Synthetic.

Use/Stability	As indicated on product label or CoA when stored as recommended.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Non-cell-autonomous cancer progression from chromosomal instability: J. Li, et al.; Nature 620, 1080 (2023), Abstract
Bisphenol A, an environmental endocrine-disrupting chemical, inhibits hypoxic response via degradation of hypoxia-inducible factor 1alpha (HIF-1alpha): structural requirement of bisphenol A for degradation of HIF-1alpha: T. Kubo, et al.; Biochem. Biophys. Res. Commun. 318, 1006 (2004), Abstract

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