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Inhibitor of caspase-3 and -7

Inhibitor of caspase-3 and caspase-7 binding to an allosteric site and not to the active site.

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Alternative Name	2-(2,4-Dichlorophenoxy)-N-(2-mercaptoethyl)acetamide
Appearance	White to off-white solid.
CAS	613665-26-2
Couple Target	Caspase, Caspase-3, Caspase-7
Couple Type	Inhibitor
Formula	C₁₀H₁₁Cl₂NO₂S
Identity	Determined by NMR.
MW	280.2
Purity	≥98% (TLC)
Solubility	Soluble in methanol or DMSO.

Use/Stability	As indicated on product label or CoA when stored as recommended. Do not store DMSO solutions for more than 1 day.
Handling	Protect from oxygen. Keep under inert gas.
Long Term Storage	-20°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

Discovery of an allosteric site in the caspases: J.A. Hardy, et al.; PNAS 101, 12461 (2004), Abstract — Full Text

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