K+ channel blocker. Blocks Kv1.2 and Kv1.1 channels (IC50=0.13 and 3.1nM in oocytes respectively, with higher values for mammalian cells), as well as heteromultimeric channels comprised of Kv1.2 and Kv1.1 with other Kv1 isoforms.
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Regulatory Status |
RUO – Research Use Only |
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