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Delphinidin chloride (high purity)

ALX-385-028

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Antioxidant

Anthocyanidin with antioxidant effect found in pigmented fruits and vegetables. Shown to inhibit angiogenesis and endothelial cell apoptosis by stimulating nitric oxide (NO) production. Inhibits solar radiation (UVB)-mediated oxidative stress, reducing DNA damage. Delphinidin induces necrosis in hepatocellular carcinoma cells with no caspase activation.

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Product Details

Appearance	Red to dark brown powder.
CAS	528-53-0
Formula	C₁₅H₁₁ClO₇
MW	338.7
Purity	≥97% (HPLC)
RTECS	DK1310000
Solubility	Soluble in water or DMSO.

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended.
Handling	Protect from light and moisture.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Cytoprotective Effects of Delphinidin for Human Chondrocytes against Oxidative Stress through Activation of Autophagy: Lee, D. Y., Park, Y. J., et al.; Antioxidants (Basel) 9, (2020), Abstract
Delphinidin Induces Necrosis in Hepatocellular Carcinoma Cells in the Presence of 3-Methyladenine, an Autophagy Inhibitor: R. Feng, et al.; J. Agric. Food Chem. 58, 3957 (2010), Abstract
Delphinidin, an anthocyanidin in pigmented fruits and vegetables, protects human HaCaT keratinocytes and mouse skin against UVB-mediated oxidative stress and apoptosis: F. Afaq, et al.; J. Invest. Dermatol. 127, 222 (2007), Abstract — Full Text
Delphinidin and cyanidin inhibit PDGF(AB)-induced VEGF release in vascular smooth muscle cells by preventing activation of p38 MAPK and JNK: M.H. Oak, et al.; Br. J. Pharmacol. 149, 283 (2006), Abstract — Full Text
Delphinidin, a dietary anthocyanidin, inhibits vascular endothelial growth factor receptor-2 phosphorylation: S. Lamy, et al.; Carcinogenesis 27, 989 (2006), Abstract — Full Text
DNA interaction with naturally occurring antioxidant flavonoids quercetin, kaempferol, and delphinidin: C.D. Kanakis, et al.; J. Biomol. Struct. Dyn. 22, 719 (2005), Abstract
Anthocyanins induce cell cycle perturbations and apoptosis in different human cell lines: M.C. Lazzè; Carcinogenesis 25, 1427 (2004), Abstract — Full Text
Delphinidin, an active compound of red wine, inhibits endothelial cell apoptosis via nitric oxide pathway and regulation of calcium homeostasis: S. Martin, et al.; Br. J. Pharmacol. 139, 1095 (2003), Abstract — Full Text

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Delphinidin chloride (high purity)

ALX-385-028

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Certificate of Analysis

SDS

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