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Cytochalasin D

BML-T109

52 citations

  • BML-T109-0001   —   1 mg
    $130.00
  • Highly pure and potent inhibitor of actin polymerization
  • Blocker of low conductance potassium channel
  • Highly cited

Cytochalasin D is a cell-permeable mycotoxin that binds to the barbed end of actin filaments inhibiting both the association and dissociation of subunits. It causes the disruption of actin filaments and inhibition of actin polymerization. As a result, it impedes with a variety of processes including cell cycle, motility, phagocytosis, proliferation, amongst others. It is about 10-fold more effective than cytochalasin B (Prod. No. BML-T108). Cytochalasin D also inactivates low conductance K+ channels, modulates CD4 cross-linking in T lymphocytes, increases intracellular Ca2+ levels, and exhibits antitumor activity.

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Regulatory Status

RUO – Research Use Only


Last modified: May 29, 2024