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- Highly pure and potent inhibitor of actin polymerization
- Blocker of low conductance potassium channel
- Highly cited
Cytochalasin D is a cell-permeable mycotoxin that binds to the barbed end of actin filaments inhibiting both the association and dissociation of subunits. It causes the disruption of actin filaments and inhibition of actin polymerization. As a result, it impedes with a variety of processes including cell cycle, motility, phagocytosis, proliferation, amongst others. It is about 10-fold more effective than cytochalasin B (Prod. No. BML-T108). Cytochalasin D also inactivates low conductance K+ channels, modulates CD4 cross-linking in T lymphocytes, increases intracellular Ca2+ levels, and exhibits antitumor activity.
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| Regulatory Status |
RUO – Research Use Only |
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Related Products
| Alternative Name | ACTA, ACTSA |
|---|---|
| Application | WB |
| Host | Rabbit |
| Species Reactivity | Bovine, Chicken, Dog, Guinea pig, Hamster, Human, Monkey, Mouse, Porcine, Rabbit, Rat, Sheep, Xenopus |
| Application | ELISA, IP, WB |
|---|---|
| Host | Rabbit |
| Isotype | IgG |
| Species Reactivity | Human, Mouse, Rat |
| Alternative Name | ACTA, ACTSA |
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| Application | ICC, WB |
| Host | Rabbit |
| Species Reactivity | Human, Mouse, Rat |
GFP-CERTIFIED® Apoptosis/Necrosis Detection kit
ENZ-51002
Multiplex assay that distinguishes between healthy, early apoptotic, late apoptotic and necrotic cells, compatible with GFP and other fluorescent probes (blue or cyan)
| Application | Flow Cytometry, Fluorescence microscopy, Fluorescent detection |
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Last modified: May 29, 2024