Cyn Monkey PPARγ Reporter Assay System

INDIGO’s Cynomolgous Monkey PPAR gamma (cPPARγ; nr1c3) Assay utilizes proprietary non-human mammalian cells engineered to provide high-level expression of cPPARγ. Reporter Cells also incorporate an cPPARγ-responsive luciferase reporter gene, therefore, quantifying expressed luciferase activity provides a sensitive surrogate measure of cPPARγ activity in the treated cells. The principle application of this reporter assay system is in the screening of test samples to quantify any functional activity, either agonist or antagonist, that they may exert against cPPARγ.