Immunologically inactive. Does not bind to immunophilin. Potent inhibitor of tumor promoting phorbol ester TPA/PMA (Prod. No. BML-PE160) in mouse skin in vivo. Potent inhibitor of Ca2+/calmodulin dependent EF-2 phosphorylation in vitro. Potent and selective antagonist of formyl peptide receptor. Inhibits formyl peptide-induced superoxide formation.
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Regulatory Status |
RUO – Research Use Only |
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