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p300 HAT activator

Potent activator of p300 HAT (histone acetyltransferase), but not of PCAF (p300/CBP-associated factor) HAT activities.

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Alternative Name	N-(4-Chloro-3-trifluoromethyl-phenyl)-2-ethoxy-6-pentadecyl-benzamide
Appearance	White to off-white crystalline solid.
CAS	586976-24-1
Couple Target	HAT
Couple Type	Activator
Formula	C₃₁H₄₃ClF₃NO₂
MW	554.1
Purity	≥97% (TLC)
Solubility	Soluble in DMSO.

Use/Stability	As indicated on product label or CoA when stored as recommended.
Handling	Protect from light.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Activation of p300 histone acetyltransferase by small molecules altering enzyme structure: probed by surface-enhanced Raman spectroscopy: K. Mantelingu, et al.; J. Phys. Chem. B. 111, 4527 (2007), Abstract

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